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Intra-articular injection of secretome, derived from umbilical cord mesenchymal stem cell, enhances the regeneration process of cartilage in early-stage osteo-arthritis: an animal study
BACKGROUND AND PURPOSE: Mesenchymal stem cells (MSCs), both endogenous and exogenous, enhance chondrocyte proliferation by stimulating collagen type II. Secretome, an MSC derivate, has shown to also provide this mechanism through a paracrine effect. We aimed to evaluate the use of secretome and MSC...
Autores principales: | LUBIS, Andri Maruli Tua, APRIANTO, Petrus, PAWITAN, Jeanne Adiwinata, PRIOSOERYANTO, Bambang Pontjo, DEWI, Tri Isyani Tungga, KAMAL, Achmad Fauzi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medical Journals Sweden, on behalf of the Nordic Orthopedic Federation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301849/ https://www.ncbi.nlm.nih.gov/pubmed/37377012 http://dx.doi.org/10.2340/17453674.2023.12359 |
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