Metabolomics and Network Analyses Reveal Phenylalanine and Tyrosine as Signatures of Anthracycline-Induced Hepatotoxicity

The chemotherapy drug doxorubicin (DOX) is an anthracycline with over 30% incidence of liver injury in breast cancer patients, yet the mechanism of its hepatotoxicity remains unclear. To identify potential biomarkers for anthracycline-induced hepatotoxicity (AIH), we generated clinically-relevant mo...

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Detalles Bibliográficos
Autores principales: Liu, Peipei, Wu, Jing, Yu, Xinyue, Guo, Linling, Zhao, Ling, Ban, Tao, Huang, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302024/
https://www.ncbi.nlm.nih.gov/pubmed/37375744
http://dx.doi.org/10.3390/ph16060797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302024/
https://www.ncbi.nlm.nih.gov/pubmed/37375744
http://dx.doi.org/10.3390/ph16060797

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