Overcoming Resistance to Immune Checkpoint Inhibitor Therapy Using Calreticulin-Inducing Nanoparticle

Nanoparticles (NPs) have the ability to transform poorly immunogenic tumors into activated ‘hot’ targets. In this study, we investigated the potential of a liposome-based nanoparticle (CRT-NP) expressing calreticulin as an in-situ vaccine to restore sensitivity to anti-CTLA4 immune checkpoint inhibi...

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Detalles Bibliográficos
Autores principales: Chandrasekar, Sri Vidhya, Singh, Akansha, Ranjan, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302072/
https://www.ncbi.nlm.nih.gov/pubmed/37376141
http://dx.doi.org/10.3390/pharmaceutics15061693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302072/
https://www.ncbi.nlm.nih.gov/pubmed/37376141
http://dx.doi.org/10.3390/pharmaceutics15061693

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