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Overcoming Resistance to Immune Checkpoint Inhibitor Therapy Using Calreticulin-Inducing Nanoparticle

Nanoparticles (NPs) have the ability to transform poorly immunogenic tumors into activated ‘hot’ targets. In this study, we investigated the potential of a liposome-based nanoparticle (CRT-NP) expressing calreticulin as an in-situ vaccine to restore sensitivity to anti-CTLA4 immune checkpoint inhibi...

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Detalles Bibliográficos
Autores principales:	Chandrasekar, Sri Vidhya, Singh, Akansha, Ranjan, Ashish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302072/ https://www.ncbi.nlm.nih.gov/pubmed/37376141 http://dx.doi.org/10.3390/pharmaceutics15061693

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