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Future Perspective for ALK-Positive Anaplastic Large Cell Lymphoma with Initial Central Nervous System (CNS) Involvement: Could Next-Generation ALK Inhibitors Replace Brain Radiotherapy for the Prevention of Further CNS Relapse?

Central nervous system (CNS) involvement in anaplastic large cell lymphoma (ALCL) at diagnosis is rare and leads to poor prognosis with the use of the standard ALCL99 protocol alone. CNS-directed intensive chemotherapy, such as an increased dose of intravenous MTX, increased dose of dexamethasone, i...

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Detalles Bibliográficos
Autores principales: Tanaka, Makito, Miura, Hiroki, Ishimaru, Soichiro, Furukawa, Gen, Kawamura, Yoshiki, Kozawa, Kei, Yamada, Seiji, Ito, Fumitaka, Kudo, Kazuko, Yoshikawa, Tetsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302098/
https://www.ncbi.nlm.nih.gov/pubmed/37368362
http://dx.doi.org/10.3390/pediatric15020029