Molecular basis and dual ligand regulation of tetrameric estrogen receptor α/14-3-3ζ protein complex

Therapeutic strategies targeting nuclear receptors (NRs) beyond their endogenous ligand binding pocket have gained significant scientific interest driven by a need to circumvent problems associated with drug resistance and pharmacological profile. The hub protein 14-3-3 is an endogenous regulator of...

Descripción completa

Detalles Bibliográficos
Autores principales: Somsen, Bente A., Sijbesma, Eline, Leysen, Seppe, Honzejkova, Karolina, Visser, Emira J., Cossar, Peter J., Obšil, Tomáš, Brunsveld, Luc, Ottmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302166/
https://www.ncbi.nlm.nih.gov/pubmed/37224961
http://dx.doi.org/10.1016/j.jbc.2023.104855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302166/
https://www.ncbi.nlm.nih.gov/pubmed/37224961
http://dx.doi.org/10.1016/j.jbc.2023.104855

Ejemplares similares