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Molecular basis and dual ligand regulation of tetrameric estrogen receptor α/14-3-3ζ protein complex

Therapeutic strategies targeting nuclear receptors (NRs) beyond their endogenous ligand binding pocket have gained significant scientific interest driven by a need to circumvent problems associated with drug resistance and pharmacological profile. The hub protein 14-3-3 is an endogenous regulator of...

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Detalles Bibliográficos
Autores principales:	Somsen, Bente A., Sijbesma, Eline, Leysen, Seppe, Honzejkova, Karolina, Visser, Emira J., Cossar, Peter J., Obšil, Tomáš, Brunsveld, Luc, Ottmann, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302166/ https://www.ncbi.nlm.nih.gov/pubmed/37224961 http://dx.doi.org/10.1016/j.jbc.2023.104855

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