Nutrient-dependent regulation of β-cell proinsulin content

Insulin is made from proinsulin, but the extent to which fasting/feeding controls the homeostatically regulated proinsulin pool in pancreatic β-cells remains largely unknown. Here, we first examined β-cell lines (INS1E and Min6, which proliferate slowly and are routinely fed fresh medium every 2–3 d...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Xiaoxi, Arunagiri, Anoop, Alam, Maroof, Haataja, Leena, Evans, Charles R., Zhao, Ivy, Castro-Gutierrez, Roberto, Russ, Holger A., Demangel, Caroline, Qi, Ling, Tsai, Billy, Liu, Ming, Arvan, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302188/
https://www.ncbi.nlm.nih.gov/pubmed/37209827
http://dx.doi.org/10.1016/j.jbc.2023.104836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302188/
https://www.ncbi.nlm.nih.gov/pubmed/37209827
http://dx.doi.org/10.1016/j.jbc.2023.104836

Ejemplares similares