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MGMT Promoter Methylation: Prognostication beyond Treatment Response

MGMT promoter methylation is related to the increased sensitivity of tumour tissue to chemotherapy with temozolomide (TMZ) and thus to improved patient survival. However, it is unclear how the extent of MGMT promoter methylation affects outcomes. In our study, a single-centre retrospective study, we...

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Detalles Bibliográficos
Autores principales: Ashkan, Keyoumars, Baig Mirza, Asfand, Soumpasis, Christos, Syrris, Christoforos, Kalaitzoglou, Dimitrios, Sharma, Chaitanya, James, Zachariah Joseph, Khoja, Abbas Khizar, Ahmed, Razna, Vastani, Amisha, Bartram, James, Chia, Kazumi, Al-Salihi, Omar, Swampilai, Angela, Brazil, Lucy, Laxton, Ross, Reisz, Zita, Bodi, Istvan, King, Andrew, Gullan, Richard, Vergani, Francesco, Bhangoo, Ranjeev, Al-Sarraj, Safa, Lavrador, Jose Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302387/
https://www.ncbi.nlm.nih.gov/pubmed/37373988
http://dx.doi.org/10.3390/jpm13060999