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Decrypting Integrins by Mixed-Solvent Molecular Dynamics Simulations

[Image: see text] Integrins are a family of α/β heterodimeric cell surface adhesion receptors which are capable of transmitting signals bidirectionally across membranes. They are known for their therapeutic potential in a wide range of diseases. However, the development of integrin-targeting medicat...

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Detalles Bibliográficos
Autores principales: Ilie, Ioana M., Ehrhardt, Claus, Caflisch, Amedeo, Weitz-Schmidt, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302478/
https://www.ncbi.nlm.nih.gov/pubmed/37310029
http://dx.doi.org/10.1021/acs.jcim.3c00480