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Large-Scale Modeling of Sparse Protein Kinase Activity Data

[Image: see text] Protein kinases are a protein family that plays an important role in several complex diseases such as cancer and cardiovascular and immunological diseases. Protein kinases have conserved ATP binding sites, which when targeted can lead to similar activities of inhibitors against dif...

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Detalles Bibliográficos
Autores principales: Luukkonen, Sohvi, Meijer, Erik, Tricarico, Giovanni A., Hofmans, Johan, Stouten, Pieter F. W., van Westen, Gerard J. P., Lenselink, Eelke B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302492/
https://www.ncbi.nlm.nih.gov/pubmed/37294674
http://dx.doi.org/10.1021/acs.jcim.3c00132