Overexpressed kinetochore genes are used by cancer cells as genome destabilizers and transformation catalysts

Cancer cells have an altered transcriptome, which contributes to their abnormal behavior. Many tumors have high levels of kinetochore genes, which play important roles in genome stability. This overexpression could be utilized to destabilize cancer cell genomes, however this has not been proven spec...

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Detalles Bibliográficos
Autores principales: Aldwaik, Reem Kamal, Shian, Denen, Thapa, Roshina, Vasudevan, Swetha, Ashqar, Mimi Abo-Ayoub, Reich, Eli, Kravchenko-Balasha, Nataly, Klutstein, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302540/
https://www.ncbi.nlm.nih.gov/pubmed/37295219
http://dx.doi.org/10.1016/j.tranon.2023.101703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302540/
https://www.ncbi.nlm.nih.gov/pubmed/37295219
http://dx.doi.org/10.1016/j.tranon.2023.101703

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