RNA demethylase ALKBH5 suppresses tumorigenesis via inhibiting proliferation and invasion and promoting CD8(+) T cell infiltration in colorectal cancer

BACKGROUND: ALKBH5 belongs to the ALKB family consists of a Fe (II) and a-ketoglutarate-dependent dioxygenase. ALKBH5 directly catalyzes the oxidative demethylation of m6A-methylated adenosine. ALKBH5 involves in tumorigenesis and tumor progression, and is often dysregulated in a wide range of cance...

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Detalles Bibliográficos
Autores principales: Ge, Jing, Liu, Sheng-Lu, Zheng, Jing-Xiu, Shi, Yu, Shao, Ying, Duan, Yu-Jing, Huang, Rui, Yang, Li-Jun, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302567/
https://www.ncbi.nlm.nih.gov/pubmed/37224767
http://dx.doi.org/10.1016/j.tranon.2023.101683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302567/
https://www.ncbi.nlm.nih.gov/pubmed/37224767
http://dx.doi.org/10.1016/j.tranon.2023.101683

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