In Silico Identification and In Vitro Validation of Repurposed Compounds Targeting the RSV Polymerase

Respiratory Syncytial Virus (RSV) is the top cause of infant hospitalization globally, with no effective treatments available. Researchers have sought small molecules to target the RNA-dependent RNA Polymerase (RdRP) of RSV, which is essential for replication and transcription. Based on the cryo-EM...

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Detalles Bibliográficos
Autores principales: Xu, Eric, Park, Seohyun, Calderon, Juan, Cao, Dongdong, Liang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302583/
https://www.ncbi.nlm.nih.gov/pubmed/37375110
http://dx.doi.org/10.3390/microorganisms11061608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302583/
https://www.ncbi.nlm.nih.gov/pubmed/37375110
http://dx.doi.org/10.3390/microorganisms11061608

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