Corneal Permeability and Uptake of Twenty-Five Drugs: Species Comparison and Quantitative Structure–Permeability Relationships

The purpose of this study was to determine corneal permeability and uptake in rabbit, porcine, and bovine corneas for twenty-five drugs using an N-in-1 (cassette) approach and relate these parameters to drug physicochemical properties and tissue thickness through quantitative structure permeability...

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Detalles Bibliográficos
Autores principales: Santana, Cleildo P., Matter, Brock A., Patil, Madhoosudan A., Silva-Cunha, Armando, Kompella, Uday B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302615/
https://www.ncbi.nlm.nih.gov/pubmed/37376094
http://dx.doi.org/10.3390/pharmaceutics15061646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302615/
https://www.ncbi.nlm.nih.gov/pubmed/37376094
http://dx.doi.org/10.3390/pharmaceutics15061646

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