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Corneal Permeability and Uptake of Twenty-Five Drugs: Species Comparison and Quantitative Structure–Permeability Relationships
The purpose of this study was to determine corneal permeability and uptake in rabbit, porcine, and bovine corneas for twenty-five drugs using an N-in-1 (cassette) approach and relate these parameters to drug physicochemical properties and tissue thickness through quantitative structure permeability...
Autores principales: | Santana, Cleildo P., Matter, Brock A., Patil, Madhoosudan A., Silva-Cunha, Armando, Kompella, Uday B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302615/ https://www.ncbi.nlm.nih.gov/pubmed/37376094 http://dx.doi.org/10.3390/pharmaceutics15061646 |
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