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Substitution of D-Arginine at Position 11 of α-RgIA Potently Inhibits α7 Nicotinic Acetylcholine Receptor

Conotoxins are a class of disulfide-rich peptides found in the venom of cone snails, which have attracted considerable attention in recent years due to their potent activity on ion channels and potential for therapeutics. Among them, α-conotoxin RgIA, a 13-residue peptide, has shown great promise as...

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Detalles Bibliográficos
Autores principales: Wu, Yong, Zhang, Junjie, Ren, Jie, Zhu, Xiaopeng, Li, Rui, Zhangsun, Dongting, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302633/
https://www.ncbi.nlm.nih.gov/pubmed/37367650
http://dx.doi.org/10.3390/md21060326