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Differential Activities of the Botanical Extract PBI-05204 and Oleandrin on Innate Immune Functions under Viral Challenge Versus Inflammatory Culture Conditions

The Nerium oleander extract PBI 05204 (PBI) and its cardiac glycoside constituent oleandrin have direct anti-viral properties. Their effect on the immune system, however, is largely unknown. We used an in vitro model of human peripheral blood mononuclear cells to document effects under three differe...

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Detalles Bibliográficos
Autores principales: Jensen, Gitte S., Yu, Liu, Iloba, Ifeanyi, Cruickshank, Dina, Matos, Jose R., Newman, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302683/
https://www.ncbi.nlm.nih.gov/pubmed/37375354
http://dx.doi.org/10.3390/molecules28124799