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Stimulation of Angiotensin II Type 2 Receptor Modulates Pro-Inflammatory Response in Microglia and Macrophages: Therapeutic Implications for the Treatment of Stroke

Background: Sustained microglial activation contributes to the development of post-stroke cognitive impairment (PSCI). Compound 21 (C21), an angiotensin II type 2 receptor agonist, has shown some neurovascular protection after stroke. This study aimed to investigate the direct anti-inflammatory effe...

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Detalles Bibliográficos
Autores principales: Alshammari, Abdulkarim, Han, Yohan, Jones, Timothy W., Pillai, Bindu, Zhang, Duo, Ergul, Adviye, Somanath, Payaningal R., Fagan, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302703/
https://www.ncbi.nlm.nih.gov/pubmed/37374057
http://dx.doi.org/10.3390/life13061274