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Stimulation of Angiotensin II Type 2 Receptor Modulates Pro-Inflammatory Response in Microglia and Macrophages: Therapeutic Implications for the Treatment of Stroke
Background: Sustained microglial activation contributes to the development of post-stroke cognitive impairment (PSCI). Compound 21 (C21), an angiotensin II type 2 receptor agonist, has shown some neurovascular protection after stroke. This study aimed to investigate the direct anti-inflammatory effe...
Autores principales: | Alshammari, Abdulkarim, Han, Yohan, Jones, Timothy W., Pillai, Bindu, Zhang, Duo, Ergul, Adviye, Somanath, Payaningal R., Fagan, Susan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302703/ https://www.ncbi.nlm.nih.gov/pubmed/37374057 http://dx.doi.org/10.3390/life13061274 |
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