In Vitro Activity of Isavuconazole and Other Mould-Active Azoles against Aspergillus fumigatus with and without CYP51 Alterations

Azole resistance in Aspergillus fumigatus (AFM) is mainly associated with mutations in CYP51A and its promoter region or its homologue CYP51B. We evaluated the in vitro activity of isavuconazole, itraconazole, posaconazole, and voriconazole against 660 AFM collected during 2017–2020. Isolates were t...

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Detalles Bibliográficos
Autores principales: Pfaller, Michael A., Carvalhaes, Cecilia G., Deshpande, Lalitagauri M., Rhomberg, Paul R., Castanheira, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302736/
https://www.ncbi.nlm.nih.gov/pubmed/37367544
http://dx.doi.org/10.3390/jof9060608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302736/
https://www.ncbi.nlm.nih.gov/pubmed/37367544
http://dx.doi.org/10.3390/jof9060608

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