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Direct Observation of Membrane-Associated H-Ras in the Native Cellular Environment by In-Cell (19)F-NMR Spectroscopy

[Image: see text] Ras acts as a molecular switch to control intracellular signaling on the plasma membrane (PM). Elucidating how Ras associates with PM in the native cellular environment is crucial for understanding its control mechanism. Here, we used in-cell nuclear magnetic resonance (NMR) spectr...

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Detalles Bibliográficos
Autores principales: Ikari, Masaomi, Yagi, Hiromasa, Kasai, Takuma, Inomata, Kohsuke, Ito, Masahiro, Higuchi, Kae, Matsuda, Natsuko, Ito, Yutaka, Kigawa, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302746/
https://www.ncbi.nlm.nih.gov/pubmed/37388687
http://dx.doi.org/10.1021/jacsau.3c00108