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AlphaFold2 and Deep Learning for Elucidating Enzyme Conformational Flexibility and Its Application for Design

[Image: see text] The recent success of AlphaFold2 (AF2) and other deep learning (DL) tools in accurately predicting the folded three-dimensional (3D) structure of proteins and enzymes has revolutionized the structural biology and protein design fields. The 3D structure indeed reveals key informatio...

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Detalles Bibliográficos
Autores principales: Casadevall, Guillem, Duran, Cristina, Osuna, Sílvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302747/
https://www.ncbi.nlm.nih.gov/pubmed/37388680
http://dx.doi.org/10.1021/jacsau.3c00188