The Effect of Ethanol on Lipid Nanoparticle Stabilization from a Molecular Dynamics Simulation Perspective

Lipid nanoparticles (LNPs) have emerged as a promising delivery system, particularly for genetic therapies and vaccines. LNP formation requires a specific mixture of nucleic acid in a buffered solution and lipid components in ethanol. Ethanol acts as a lipid solvent, aiding the formation of the nano...

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Detalles Bibliográficos
Autores principales: Hardianto, Ari, Muscifa, Zahra Silmi, Widayat, Wahyu, Yusuf, Muhammad, Subroto, Toto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302858/
https://www.ncbi.nlm.nih.gov/pubmed/37375391
http://dx.doi.org/10.3390/molecules28124836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302858/
https://www.ncbi.nlm.nih.gov/pubmed/37375391
http://dx.doi.org/10.3390/molecules28124836

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