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The Effect of Ethanol on Lipid Nanoparticle Stabilization from a Molecular Dynamics Simulation Perspective
Lipid nanoparticles (LNPs) have emerged as a promising delivery system, particularly for genetic therapies and vaccines. LNP formation requires a specific mixture of nucleic acid in a buffered solution and lipid components in ethanol. Ethanol acts as a lipid solvent, aiding the formation of the nano...
Autores principales: | Hardianto, Ari, Muscifa, Zahra Silmi, Widayat, Wahyu, Yusuf, Muhammad, Subroto, Toto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302858/ https://www.ncbi.nlm.nih.gov/pubmed/37375391 http://dx.doi.org/10.3390/molecules28124836 |
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