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Background-Quenched Aggregation-Induced Emission through Electrostatic Interactions for the Detection of Poly(ADP-ribose) Polymerase-1 Activity

Poly(ADP-ribose) polymerase-1 (PARP1) is a potential biomarker and therapeutic target for cancers that can catalyze the poly-ADP-ribosylation of nicotinamide adenine dinucleotide (NAD(+)) onto the acceptor proteins to form long poly(ADP-ribose) (PAR) polymers. Through integration with aggregation-in...

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Detalles Bibliográficos
Autores principales: Gao, Fengli, Zhao, Ruimin, Huang, Liping, Yi, Xinyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302931/
https://www.ncbi.nlm.nih.gov/pubmed/37375313
http://dx.doi.org/10.3390/molecules28124759