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Clorgyline Analogs Synergize with Azoles against Drug Efflux in Candida auris

Concern about the global emergence of multidrug-resistant fungal pathogens led us to explore the use of combination therapy to combat azole resistance in Candida auris. Clorgyline had previously been shown to be a multi-target inhibitor of Cdr1 and Mdr1 efflux pumps of Candida albicans and Candida g...

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Detalles Bibliográficos
Autores principales: Toepfer, Stephanie, Lackner, Michaela, Keniya, Mikhail V., Zenz, Lisa-Maria, Friemert, Marianne, Bracher, Franz, Monk, Brian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303049/
https://www.ncbi.nlm.nih.gov/pubmed/37367600
http://dx.doi.org/10.3390/jof9060663