Conjugation of Triterpenic Acids of Ursane and Oleanane Types with Mitochondria-Targeting Cation F16 Synergistically Enhanced Their Cytotoxicity against Tumor Cells

The present work shows the cytotoxic effects of novel conjugates of ursolic, oleanolic, maslinic, and corosolic acids with the penetrating cation F16 on cancer cells (lung adenocarcinoma A549 and H1299, breast cancer cell lines MCF-7 and BT474) and non-tumor human fibroblasts. It has been establishe...

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Detalles Bibliográficos
Autores principales: Dubinin, Mikhail V., Nedopekina, Darya A., Ilzorkina, Anna I., Semenova, Alena A., Sharapov, Vyacheslav A., Davletshin, Eldar V., Mikina, Natalia V., Belsky, Yuri P., Spivak, Anna Yu., Akatov, Vladimir S., Belosludtseva, Natalia V., Liu, Jiankang, Belosludtsev, Konstantin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303159/
https://www.ncbi.nlm.nih.gov/pubmed/37367767
http://dx.doi.org/10.3390/membranes13060563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303159/
https://www.ncbi.nlm.nih.gov/pubmed/37367767
http://dx.doi.org/10.3390/membranes13060563

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