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VSV-ΔG-Spike Candidate Vaccine Induces Protective Immunity and Protects K18-hACE2 Mice against SARS-CoV-2 Variants

Since the emergence of the original SARS-CoV-2, several variants were described, raising questions as to the ability of recently developed vaccine platforms to induce immunity and provide protection against these variants. Here, we utilized the K18-hACE2 mouse model to show that VSV-ΔG-spike vaccina...

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Detalles Bibliográficos
Autores principales: Yahalom-Ronen, Yfat, Tamir, Hadas, Melamed, Sharon, Politi, Boaz, Achdout, Hagit, Erez, Noam, Israeli, Ofir, Cohen-Gihon, Inbar, Chery Mimran, Lilach, Barlev-Gross, Moria, Mandelboim, Michal, Orr, Irit, Feldmesser, Ester, Weiss, Shay, Beth-Din, Adi, Paran, Nir, Israely, Tomer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303402/
https://www.ncbi.nlm.nih.gov/pubmed/37376662
http://dx.doi.org/10.3390/v15061364