Annexin A5 Inhibits Endothelial Inflammation Induced by Lipopolysaccharide-Activated Platelets and Microvesicles via Phosphatidylserine Binding

Sepsis is caused by a dysregulated immune response to infection and is a leading cause of mortality globally. To date, no specific therapeutics are available to treat the underlying septic response. We and others have shown that recombinant human annexin A5 (Anx5) treatment inhibits pro-inflammatory...

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Detalles Bibliográficos
Autores principales: Tschirhart, Brent J., Lu, Xiangru, Gomes, Janice, Chandrabalan, Arundhasa, Bell, Gillian, Hess, David A., Xing, Guangxin, Ling, Hong, Burger, Dylan, Feng, Qingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303431/
https://www.ncbi.nlm.nih.gov/pubmed/37375784
http://dx.doi.org/10.3390/ph16060837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303431/
https://www.ncbi.nlm.nih.gov/pubmed/37375784
http://dx.doi.org/10.3390/ph16060837

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