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Annexin A5 Inhibits Endothelial Inflammation Induced by Lipopolysaccharide-Activated Platelets and Microvesicles via Phosphatidylserine Binding
Sepsis is caused by a dysregulated immune response to infection and is a leading cause of mortality globally. To date, no specific therapeutics are available to treat the underlying septic response. We and others have shown that recombinant human annexin A5 (Anx5) treatment inhibits pro-inflammatory...
Autores principales: | Tschirhart, Brent J., Lu, Xiangru, Gomes, Janice, Chandrabalan, Arundhasa, Bell, Gillian, Hess, David A., Xing, Guangxin, Ling, Hong, Burger, Dylan, Feng, Qingping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303431/ https://www.ncbi.nlm.nih.gov/pubmed/37375784 http://dx.doi.org/10.3390/ph16060837 |
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