Design and Synthesis of New 4-(3,4,5-Trimethoxyphenyl)Thiazole–Pyrimidine Derivatives as Potential Antiproliferative Agents

A new series of 3,4,5-trimethoxyphenyl thiazole pyrimidines has been synthesized and biologically evaluated for its in vitro anticancer activity. Compounds 4a, 4b, and 4h with substituted piperazine showed the best antiproliferative activity. In the NCI-60 cell line screening, compound 4b showed pro...

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Detalles Bibliográficos
Autores principales: El-Damasy, Ashraf K., Jin, Heewon, Sabry, Mohamed A., Kim, Hyun Ji, Alanazi, Mohammed M., Seo, Seon Hee, Bang, Eun-Kyoung, Keum, Gyochang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303439/
https://www.ncbi.nlm.nih.gov/pubmed/37374282
http://dx.doi.org/10.3390/medicina59061076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303439/
https://www.ncbi.nlm.nih.gov/pubmed/37374282
http://dx.doi.org/10.3390/medicina59061076

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