Diversity of Solid Forms Promoted by Ball Milling: Characterization and Intrinsic Dissolution Studies of Pioglitazone Hydrochloride and Fluvastatin Sodium Drug–Drug Systems

Coamorphous salt in a 1:1 ratio prepared by ball milling from Fluvastatin sodium (FLV) and Pioglitazone hydrochloride (PGZ·HCl) can be selectively formed by neat grinding (NG). Furthermore, the salt–cocrystal continuum was preferably formed by employing liquid-assisted grinding (LAG) using ethanol (...

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Detalles Bibliográficos
Autores principales: Villeda-Villegas, Marco, Páez-Franco, José C., Coyote-Dotor, Guadalupe, Núñez-Pineda, Alejandra, Dorazco-González, Alejandro, Fuentes-Noriega, Inés, Rubio-Carrasco, Kenneth, Toledo Jaldín, Helen P., Morales-Morales, David, Germán-Acacio, Juan Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303448/
https://www.ncbi.nlm.nih.gov/pubmed/37375729
http://dx.doi.org/10.3390/ph16060781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303448/
https://www.ncbi.nlm.nih.gov/pubmed/37375729
http://dx.doi.org/10.3390/ph16060781

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