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Diversity of Solid Forms Promoted by Ball Milling: Characterization and Intrinsic Dissolution Studies of Pioglitazone Hydrochloride and Fluvastatin Sodium Drug–Drug Systems
Coamorphous salt in a 1:1 ratio prepared by ball milling from Fluvastatin sodium (FLV) and Pioglitazone hydrochloride (PGZ·HCl) can be selectively formed by neat grinding (NG). Furthermore, the salt–cocrystal continuum was preferably formed by employing liquid-assisted grinding (LAG) using ethanol (...
Autores principales: | Villeda-Villegas, Marco, Páez-Franco, José C., Coyote-Dotor, Guadalupe, Núñez-Pineda, Alejandra, Dorazco-González, Alejandro, Fuentes-Noriega, Inés, Rubio-Carrasco, Kenneth, Toledo Jaldín, Helen P., Morales-Morales, David, Germán-Acacio, Juan Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303448/ https://www.ncbi.nlm.nih.gov/pubmed/37375729 http://dx.doi.org/10.3390/ph16060781 |
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