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Study of the roles of caspase-3 and nuclear factor kappa B in myenteric neurons in a P2X7 receptor knockout mouse model of ulcerative colitis

BACKGROUND: The literature indicates that the enteric nervous system is affected in inflammatory bowel diseases (IBDs) and that the P2X7 receptor triggers neuronal death. However, the mechanism by which enteric neurons are lost in IBDs is unknown. AIM: To study the role of the caspase-3 and nuclear...

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Detalles Bibliográficos
Autores principales: Magalhães, Henrique Inhauser Riceti, Machado, Felipe Alexandre, Souza, Roberta Figueiroa, Caetano, Marcos Antônio Ferreira, Figliuolo, Vanessa Ribeiro, Coutinho-Silva, Robson, Castelucci, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303518/
https://www.ncbi.nlm.nih.gov/pubmed/37389242
http://dx.doi.org/10.3748/wjg.v29.i22.3440