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Visualization and Estimation of Nasal Spray Delivery to Olfactory Mucosa in an Image-Based Transparent Nasal Model

Background: Nose-to-brain (N2B) drug delivery offers unique advantages over intravenous methods; however, the delivery efficiency to the olfactory region using conventional nasal devices and protocols is low. This study proposes a new strategy to effectively deliver high doses to the olfactory regio...

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Detalles Bibliográficos
Autores principales: Seifelnasr, Amr, Si, Xiuhua April, Xi, Jinxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303528/
https://www.ncbi.nlm.nih.gov/pubmed/37376105
http://dx.doi.org/10.3390/pharmaceutics15061657