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Vincamine Ameliorates Epithelial-Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis in Rats; Targeting TGF-β/MAPK/Snai1 Pathway

Idiopathic pulmonary fibrosis is a progressive, irreversible lung disease that leads to respiratory failure and death. Vincamine is an indole alkaloid obtained from the leaves of Vinca minor and acts as a vasodilator. The present study aims to investigate the protective activity of vincamine against...

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Detalles Bibliográficos
Autores principales: Alaaeldin, Rania, Mohyeldin, Reham H., Bekhit, Amany Abdlrehim, Gomaa, Wafaey, Zhao, Qing-Li, Fathy, Moustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303541/
https://www.ncbi.nlm.nih.gov/pubmed/37375218
http://dx.doi.org/10.3390/molecules28124665