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A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase

DNA-mimicking proteins encoded by viruses can modulate processes such as innate cellular immunity. An example is Ung-family uracil-DNA glycosylase inhibition, which prevents Ung-mediated degradation via the stoichiometric protein blockade of the Ung DNA-binding cleft. This is significant where uraci...

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Detalles Bibliográficos
Autores principales: Muselmani, Wael, Kashif-Khan, Naail, Bagnéris, Claire, Santangelo, Rosalia, Williams, Mark A., Savva, Renos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303552/
https://www.ncbi.nlm.nih.gov/pubmed/37376646
http://dx.doi.org/10.3390/v15061348