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A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase
DNA-mimicking proteins encoded by viruses can modulate processes such as innate cellular immunity. An example is Ung-family uracil-DNA glycosylase inhibition, which prevents Ung-mediated degradation via the stoichiometric protein blockade of the Ung DNA-binding cleft. This is significant where uraci...
Autores principales: | Muselmani, Wael, Kashif-Khan, Naail, Bagnéris, Claire, Santangelo, Rosalia, Williams, Mark A., Savva, Renos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303552/ https://www.ncbi.nlm.nih.gov/pubmed/37376646 http://dx.doi.org/10.3390/v15061348 |
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