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The Selective LAT1 Inhibitor JPH203 Enhances Mitochondrial Metabolism and Content in Insulin-Sensitive and Insulin-Resistant C2C12 Myotubes

Population data have shown an association between higher circulating branched-chain amino acids (BCAA) and the severity of insulin resistance in people with diabetes. While several studies have assessed BCAA metabolism as a potential target for regulation, less attention has been paid to the role of...

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Detalles Bibliográficos
Autores principales: Rivera, Caroline N., Smith, Carly E., Draper, Lillian V., Ochoa, Gabriela E., Watne, Rachel M., Wommack, Andrew J., Vaughan, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303577/
https://www.ncbi.nlm.nih.gov/pubmed/37367923
http://dx.doi.org/10.3390/metabo13060766