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An Integrated Computational Analysis of High-Risk SNPs in Angiopoietin-like Proteins (ANGPTL3 and ANGPTL8) Reveals Perturbed Protein Dynamics Associated with Cancer

Angiopoietin-like proteins (ANGPTL) constitute a family of eight proteins (1–8) which play a pivotal role in the regulation of various pathophysiological processes. The current study sought to identify high-risk, “non-synonymous, single-nucleotide polymorphisms” (nsSNPs) in both ANGPTL3 and ANGPTL8...

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Detalles Bibliográficos
Autores principales: Iqbal, Sajid, Begum, Farida, Nyamai, Dorothy Wavinya, Jalal, Nasir, Shaw, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303706/
https://www.ncbi.nlm.nih.gov/pubmed/37375208
http://dx.doi.org/10.3390/molecules28124648