Development and Evaluation of Self-Microemulsifying Drug Delivery System for Improving Oral Absorption of Poorly Water-Soluble Olaparib

The purpose of this study is to develop and evaluate a self-microemulsifying drug delivery system (SMEDDS) to improve the oral absorption of poorly water-soluble olaparib. Through the solubility test of olaparib in various oils, surfactants and co-surfactants, pharmaceutical excipients were selected...

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Detalles Bibliográficos
Autores principales: Kim, Yong-Han, Kim, Seong-Bo, Choi, Se-Hee, Nguyen, Thi-Thao-Linh, Ahn, Sung-Hoon, Moon, Kyung-Sun, Cho, Kwan-Hyung, Sim, Tae-Yong, Heo, Eun-Ji, Kim, Sung Tae, Jung, Hyun-Suk, Jee, Jun-Pil, Choi, Han-Gon, Jang, Dong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303741/
https://www.ncbi.nlm.nih.gov/pubmed/37376117
http://dx.doi.org/10.3390/pharmaceutics15061669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303741/
https://www.ncbi.nlm.nih.gov/pubmed/37376117
http://dx.doi.org/10.3390/pharmaceutics15061669

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