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Stem cell-derived brainstem mouse astrocytes obtain a neurotoxic phenotype in vitro upon neuroinflammation

BACKGROUND: Astrocytes respond to injury and disease through a process known as reactive astrogliosis, of which inflammatory signaling is one subset. This inflammatory response is heterogeneous with respect to the inductive stimuli and the afflicted central nervous system region. This is of plausibl...

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Detalles Bibliográficos
Autores principales: Lindblad, Caroline, Neumann, Susanne, Kolbeinsdóttir, Sólrún, Zachariadis, Vasilios, Thelin, Eric P., Enge, Martin, Thams, Sebastian, Brundin, Lou, Svensson, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303821/
https://www.ncbi.nlm.nih.gov/pubmed/37370141
http://dx.doi.org/10.1186/s12950-023-00349-8