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Polyphyllin I suppressed the apoptosis of intervertebral disc nucleus pulposus cells induced by IL-1β by miR-503-5p/Bcl-2 axis

BACKGROUND: There are no studies that have shown the role and underlying mechanism of Polyphyllin I (PPI)-mediated anti-apoptosis activity in nucleus pulposus cells (NPCs). The research aimed to evaluate the effects of PPI in interleukin (IL)-1β-induced NPCs apoptosis in vitro. METHODS: Cell Countin...

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Detalles Bibliográficos
Autores principales: Yuan, Lei, Miao, Hui, Ding, Heng, Zhang, Fan, Lou, Zhen-kai, Li, Xing-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303845/
https://www.ncbi.nlm.nih.gov/pubmed/37380996
http://dx.doi.org/10.1186/s13018-023-03947-7