Cargando…
Polyphyllin I suppressed the apoptosis of intervertebral disc nucleus pulposus cells induced by IL-1β by miR-503-5p/Bcl-2 axis
BACKGROUND: There are no studies that have shown the role and underlying mechanism of Polyphyllin I (PPI)-mediated anti-apoptosis activity in nucleus pulposus cells (NPCs). The research aimed to evaluate the effects of PPI in interleukin (IL)-1β-induced NPCs apoptosis in vitro. METHODS: Cell Countin...
Autores principales: | Yuan, Lei, Miao, Hui, Ding, Heng, Zhang, Fan, Lou, Zhen-kai, Li, Xing-Guo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303845/ https://www.ncbi.nlm.nih.gov/pubmed/37380996 http://dx.doi.org/10.1186/s13018-023-03947-7 |
Ejemplares similares
-
miR-222 induces apoptosis in human intervertebral disc nucleus pulposus cells by targeting Bcl-2
por: Wang, Wei, et al.
Publicado: (2019) -
Effect of Fas and Bcl-2 DNA Damages Response Expression in Stem Cells on Apoptosis of Nucleus Pulposus of Intervertebral Disc
por: Zhang, Hui, et al.
Publicado: (2023) -
Expression of miR-195 and its target gene Bcl-2 in human intervertebral disc degeneration and their effects on nucleus pulposus cell apoptosis
por: Lin, Xue-Lin, et al.
Publicado: (2021) -
Senescence of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs
por: Kim, Ki-Won, et al.
Publicado: (2008) -
Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc
por: Rajasekaran, Shanmuganathan, et al.
Publicado: (2020)