Discovery of a New Chalcone-Trimethoxycinnamide Hybrid with Antimitotic Effect: Design, Synthesis, and Structure—Activity Relationship Studies

In this work, the design and synthesis of a new chalcone-trimethoxycinnamide hybrid (7) based on the combination of subunits of two promising antiproliferative compounds (CM-M345 (1) and BP-M345 (2)), previously obtained by our research group, are reported. In order to expand the structure–activity...

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Detalles Bibliográficos
Autores principales: Moreira, Joana, Silva, Patrícia M. A., Barros, Matilde, Saraiva, Lucília, Pinto, Madalena, Bousbaa, Hassan, Cidade, Honorina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303900/
https://www.ncbi.nlm.nih.gov/pubmed/37375826
http://dx.doi.org/10.3390/ph16060879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303900/
https://www.ncbi.nlm.nih.gov/pubmed/37375826
http://dx.doi.org/10.3390/ph16060879

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