Competition between skin antimicrobial peptides and commensal bacteria in type 2 inflammation enables survival of S. aureus

During inflammation, the skin deploys antimicrobial peptides (AMPs) yet during allergic inflammation it becomes more susceptible to Staphylococcus aureus. To understand this contradiction, single-cell sequencing of Il4ra(−/−) mice combined with skin microbiome analysis reveals that lower production...

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Detalles Bibliográficos
Autores principales: Nakatsuji, Teruaki, Brinton, Samantha L., Cavagnero, Kellen J., O’Neill, Alan M., Chen, Yang, Dokoshi, Tatsuya, Butcher, Anna M., Osuoji, Olive C., Shafiq, Faiza, Espinoza, Josh L., Dupont, Christopher L., Hata, Tissa R., Gallo, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303920/
https://www.ncbi.nlm.nih.gov/pubmed/37167061
http://dx.doi.org/10.1016/j.celrep.2023.112494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303920/
https://www.ncbi.nlm.nih.gov/pubmed/37167061
http://dx.doi.org/10.1016/j.celrep.2023.112494

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