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Competition between skin antimicrobial peptides and commensal bacteria in type 2 inflammation enables survival of S. aureus
During inflammation, the skin deploys antimicrobial peptides (AMPs) yet during allergic inflammation it becomes more susceptible to Staphylococcus aureus. To understand this contradiction, single-cell sequencing of Il4ra(−/−) mice combined with skin microbiome analysis reveals that lower production...
Autores principales: | Nakatsuji, Teruaki, Brinton, Samantha L., Cavagnero, Kellen J., O’Neill, Alan M., Chen, Yang, Dokoshi, Tatsuya, Butcher, Anna M., Osuoji, Olive C., Shafiq, Faiza, Espinoza, Josh L., Dupont, Christopher L., Hata, Tissa R., Gallo, Richard L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303920/ https://www.ncbi.nlm.nih.gov/pubmed/37167061 http://dx.doi.org/10.1016/j.celrep.2023.112494 |
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