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Synthesis and Modification of Morphine and Codeine, Leading to Diverse Libraries with Improved Pain Relief Properties

Morphine and codeine, two of the most common opioids, are widely used in the clinic for different types of pain. Morphine is one of the most potent agonists for the μ-opioid receptor, leading to the strongest analgesic effect. However, due to their association with serious side effects such as respi...

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Detalles Bibliográficos
Autores principales: Zarin, Mona Kamelan Zargar, Dehaen, Wim, Salehi, Peyman, Asl, Amir Ata Bahmani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304093/
https://www.ncbi.nlm.nih.gov/pubmed/37376226
http://dx.doi.org/10.3390/pharmaceutics15061779