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Development of Zeise’s Salt Derivatives Bearing Substituted Acetylsalicylic Acid Substructures as Cytotoxic COX Inhibitors

Zeise’s salt derivatives of the potassium trichlorido[η(2)-((prop-2-en/but-3-en)-1-yl)-2-acetoxybenzoate]platinate(II) type (ASA-Prop-PtCl(3)/ASA-But-PtCl(3) derivatives) were synthesized and characterized regarding their structure, stability, and biological activity. It is proposed that the leads A...

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Detalles Bibliográficos
Autores principales: Weninger, Alexander, Sagasser, Jessica, Obermoser, Victoria, Egger, Josef, Wisboeck, Susanna, Qiu, Qianqian, Ladstaetter, Miriam, Cucchiaro, Andrea, Wurst, Klaus, Baecker, Daniel, Gust, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304174/
https://www.ncbi.nlm.nih.gov/pubmed/37376023
http://dx.doi.org/10.3390/pharmaceutics15061573